Familial chylomicronemia syndrome (FCS) is a serious inherited lipid disorder with chronic, life-altering consequences.
FCS is a genetic condition that causes a buildup of fats in the blood that can increase the risk of severe abdominal pain and potentially fatal attacks of pancreatitis. It is also sometimes known as lipoprotein lipase deficiency (LPLD), Fredrickson Type 1 hyperlipoproteinemia and familial hypertriglyceridemia. Most patients take steps to reduce their risk of pancreatitis through lifestyle modifications including strictly limiting fat intake.
FCS occurs in about 1 in 1 million people and the genetic disorder causes the body to not be able to break down certain fats correctly. This disease frequently leads to symptoms such as pancreatitis — a very serious condition that causes inflammation of the pancreas and can lead to death – and fatty deposits in the skin.